Overexpression of a Slit Homologue Impairs Convergent Extension of the Mesoderm and Causes Cyclopia in Embryonic Zebrafish
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چکیده
منابع مشابه
Overexpression of a slit homologue impairs convergent extension of the mesoderm and causes cyclopia in embryonic zebrafish.
Slit is expressed in the midline of the central nervous system both in vertebrates and invertebrates. In Drosophila, it is the midline repellent acting as a ligand for the Roundabout (Robo) protein, the repulsive receptor which is expressed on the growth cones of the commissural neurons. We have isolated cDNA fragments of the zebrafish slit2 and slit3 homologues and found that both genes start ...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2001
ISSN: 0012-1606
DOI: 10.1006/dbio.2000.0105